Sertraline

Sertraline is a drug in the serotonin reuptake inhibitor class used to treat various mental conditions. It is available under different brand names worldwide. This article includes its uses, side effects, dosage, and popular brand names.

What is Sertraline?

Sertraline is a selective serotonin reuptake inhibitor (SSRI) that is used as an antidepressant. It has the following uses:

1. Depression
2. Anxiety disorders
3. Obsessive-compulsive disorder (OCD)
4. Post-traumatic stress disorder (PTSD)
5. Social anxiety disorder
6. Panic disorder

It increases serotonin levels, a neurotransmitter that regulates the mood in the human brain.

Mechanism of action of Sertraline

It works by maintaining and balancing the level of serotonin in the brain. By inhibiting the reuptake of serotonin, it allows more serotonin to be available, which can improve mood, reduce anxiety, and help control compulsive behaviors.

Uses of Sertraline

1. Depression

Most of the time sertraline is prescribed for patients with major depressive disorder (MDD). It helps to alleviate symptoms like persistent sadness, fatigue, and lack of interest in daily activities.

2. Anxiety Disorders

It is also used to manage generalized anxiety disorder (GAD) and social anxiety disorder, reducing feelings of nervousness, tension, and fear.

3. Obsessive-Compulsive Disorder (OCD)

Sertraline can help reduce the intensity and frequency of obsessive thoughts and compulsive behaviors that individuals with OCD experience.

4. Panic Disorder

It is effective in managing panic attacks and the constant fear of future attacks that people with panic disorder often face.

5. PTSD

It helps to manage symptoms such as flashbacks and hypervigilance. Thus it is for the treatment of patients with post-traumatic stress disorder.

Dosage of Sertraline

The typical starting dose of sertraline is 50 mg per day, which may be gradually increased depending on the individual’s response and tolerance. The maximum dose of sertraline is 200 mg/day.

How to Take Sertraline

• Oral tablet

It is usually taken once a day, with or without food.

• Liquid form

If prescribed, the liquid form is measured with a dose-measuring spoon or syringe.

Important Instructions

• Take sertraline at the same time each day to help remember.
• Don’t stop it at once without consulting your healthcare provider.
• Regular follow-up visits with your doctor are important to monitor progress and adjust dosage.

Side Effects of Sertraline

Common Side Effects

• Nausea
• Insomnia
• Drowsiness
• Dry mouth
• Sweating
• Sexual dysfunction (decreased libido, difficulty achieving orgasm)

Serious Side Effects

• Suicidal attempts thoughts or especially in young adults and adolescents.
• Serotonin syndrome (symptoms include agitation, hallucinations, and rapid heartbeat)
• Unusual bleeding or bruising

Contraindications

• Individuals who are allergic to sertraline or any of its ingredients.
• People taking monoamine oxidase inhibitors (MAOIs) or within two weeks of discontinuing them.
• Pregnant or breastfeeding women should consult a doctor before using it.

Sertraline Brand Names

Here is a table outlining some of the most popular brand names of sertraline and their specifications:

Brand Name	Form	Dosage	Manufacturer
Zoloft	Oral tablet, Liquid	25 mg – 200 mg	Pfizer
Lustral	Oral tablet	50 mg – 100 mg	GlaxoSmithKline
Serlain	Oral tablet	25 mg – 100 mg	Mylan
Sertraline Actavis	Oral tablet	50 mg – 100 mg	Actavis
Stimuloton	Oral tablet	50 mg – 100 mg	Torrent Pharmaceuticals

Conclusion

Sertraline is an effective treatment option for various mental health conditions. While it is generally well-tolerated, patients should be aware of potential side effects and consult a doctor regularly to ensure it’s the right choice for them. However, it’s crucial to follow the prescribed dosage and stay in communication with a healthcare provider throughout the treatment process.