Glibenclamide, also known as glyburide, is an oral hypoglycemic agent commonly used in the management of Type 2 diabetes mellitus. It belongs to the class of drugs called sulfonylureas and works by stimulating insulin release from the pancreas. Mechanism of Action Insulin Release Stimulation Glibenclamide binds to specific receptors on …
Read More »Sulfonylureas to manage type 2 diabetes mellitus
Sulfonylureas are a class of oral antidiabetic medications primarily used to manage type 2 diabetes mellitus. They work by stimulating the pancreas to release more insulin, thereby helping to control blood sugar levels. Mechanism of Action Sulfonylureas exert their effect by binding to specific receptors on the pancreatic beta cells, …
Read More »Understanding the Importance of Insulin in Diabetes
Insulin is one of the most crucial hormones in the body, especially for individuals with diabetes. It regulates blood sugar levels and is essential for maintaining overall health. This article provides a thorough understanding of insulin, including its definition, importance, manufacturing process, various types, uses, side effects, and safety precautions. …
Read More »Antidiabetic Drugs – Anti-hyperglycemic drugs
Diabetes mellitus is a chronic disease characterized by elevated blood glucose levels, resulting from either a lack of insulin production (Type 1 diabetes) or resistance to insulin (Type 2 diabetes). Proper management of diabetes involves lifestyle modifications and the use of pharmacological agents to control blood sugar levels. There are …
Read More »Vasodilation Medications -A Class of Antihypertensive Drugs
Vasodilators for high blood pressure are a vital class of drugs used to manage high blood pressure (hypertension) and other cardiovascular conditions. These medications work by relaxing and expanding blood vessels, allowing blood to flow more easily, which reduces the heart’s workload. This article delves into the uses, side …
Read More »Angiotensin Receptor Blockers (ARBs)
Angiotensin Receptor Blockers (ARBs) are a class of drugs that help treat conditions like hypertension, heart failure, chronic kidney disease, and stroke prevention. They work by blocking the action of angiotensin II, a hormone that can constrict blood vessels, raising blood pressure. Mechanism of Action ARBs target and block the …
Read More »Alpha Blockers: Types, Uses, Side Effects, Drug Interactions, and Contraindications
Alpha blockers, or alpha-adrenergic antagonists, are a class of medications that block alpha receptors in the body. These receptors are involved in regulating the contraction of smooth muscles, particularly in blood vessels and other tissues like the prostate. By blocking these receptors, α- blockers help treat various medical conditions, such as …
Read More »ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors)
ACE Inhibitors (Angiotensin-Converting Enzyme Inhibitors) inhibit ACE, preventing the conversion of angiotensin I to angiotensin II, a substance that narrows blood vessels. As a result, it causes vasodilation, reduces blood pressure, and decreases the workload on the heart. Common Uses 1. Hypertension (High Blood Pressure) 2. Heart Failure 3. Chronic …
Read More »Calcium Channel Blockers (CCBs) or Calcium Antagonists
Calcium channel blockers (CCBs), also known as calcium antagonists, are a class of antihypertensive medications used to manage high blood pressure (hypertension) and other cardiovascular conditions. These drugs help in the treatment of various heart-related issues by regulating the amount of calcium that enters cells. Common Names and Brand Names …
Read More »Beta Blockers – Uses, Side Effects, Risks & More
Beta blockers are a class of antihypertensive medications primarily used to manage heart conditions like high blood pressure (hypertension), heart failure, and arrhythmias. β blockers work by blocking the effects of adrenaline on beta receptors, reducing heart rate and blood pressure. Common Beta Blockers & Popular Brands Propranolol Brand Names: …
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