Adalimumab (Humira) is a biological medication used for the treatment and management of several inflammatory disorders. It targets and inhibits tumor necrosis factor-alpha (TNF-α), a cytokine that plays an important role in systemic inflammation. The inhibition of TNF-α by adalimumab leads to a decrease in inflammation, alleviation of pain, and mitigation of tissue damage. This…
Category: Drug Information
50 common and harmful drug and drug interactions Drug and drug interactions PDF file Drug Interactions- PDF Free Download Here is the table of the most frequent and harmful drug and drug interactions at clinical setups. Drug 1 Drug 2 Interaction Type Mechanism/Effect Potential Harm Mebendazole Metronidazole Increased toxicity Metronidazole inhibits the metabolism of mebendazole.…
Sulfasalazine is a drug used to treat inflammatory bowel diseases (IBD) and autoimmune disorders. It has both anti-inflammatory and immunosuppressive effects, that make it effective in managing conditions such as ulcerative colitis, rheumatoid arthritis, and Crohn’s disease. Mechanism of Action Sulfasalazine is a prodrug because it requires metabolic activation to become effective. Once it is…
UseHydroxychloroquine is a drug used to treat malaria, autoimmune diseases like lupus, and rheumatoid arthritis. In recent years, it has been proposed that it may have a significant role in treating COVID-19, though its efficacy is not approved and is under research studies. Hydroxychloroquine is an anti-malarial drug from the class of drugs disease-modifying anti-rheumatic…
Methotrexate is a well-known medication used to treat various autoimmune diseases and cancers. It is listed as a disease-modifying antirheumatic drug (DMARD) and chemotherapy agent. Below is a detailed drug profile, including its uses, side effects, and popular brand names. What is Methotrexate? Methotrexate is a folate antagonist that inhibits the enzyme dihydrofolate reductase. It…
Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) used for relieving pain, reducing inflammation, and managing symptoms of various conditions like arthritis. It is available over the counter (OTC) and also by prescription. Chemical Composition & Properties Generic Name: Naproxen sodium Chemical Formula: C14H13NaO3 Molecular Weight: 252.24 g/mol Drug Class: NSAID (Nonsteroidal Anti-Inflammatory Drug) Solubility:…
Quetiapine is an atypical antipsychotic drug. It is widely prescribed for treating conditions like schizophrenia, bipolar disorder, and depression. Quetiapine is available in both immediate-release and extended-release formulations. Mechanism of Action Quetiapine performs its work by altering neurotransmitter activity in the brain. It affects the following receptors. Dopamine D2 receptors: Reduces psychotic symptoms. Serotonin 5-HT2A…
Propranolol, a beta blocker is a medication used for the management and treatment of various cardiovascular conditions, including hypertension, angina, and arrhythmias, and also for anxiety and migraine prevention. This comprehensive drug profile outlines the key aspects of propranolol, including its mechanism of action, indications, dosage, side effects, and more. Mechanism of Action Beta-Adrenergic Blockade:…
Orphenadrine Citrate is a muscle relaxant that works by blocking nerve impulses to reduce muscle spasms. It belongs to the class of drugs known as anticholinergics used to treat muscle spasms and pain. This article will explore its uses, side effects, precautions, drug interactions, dosage, combination drugs, and popular brand names. Uses of Orphenadrine Citrate…